Category Property Value Genomics Gene Name Hg_chrom6_TN10gene_11621 Genomics Gene Locus chr6:6282678-6302771 Genomics Nested Gene Genomics (host gene) Genomics Average 1 Genomics TN7 1 Genomics TN8 1 Genomics TN10 1 Genomics TN20 1 Genomics TN22 1 Genomics MM26 1 Genomics OP50 1 Genomics PA3 1 Genomics X12 1 Effectors SCN putative Effectors SCN known (N) Effectors SCN known (P) Effectors BCN known Effectors BCN putative Effectors Effector Islands Effectors Cluster Name 11-Not_Clustered Effectors (score) 0.7580 Secretion Secretion membrane_bound Secretion DL-signals signal_peptide|transmembrane_domain Secretion DL-localization cell_membrane Secretion Localizer Secretion L-nucleus Secretion L-mitochondria Secretion (score) Secretion L-chloroplast Secretion (score) Secretion Signal Peptide 1-33 Secretion (score_v5) Secretion (score_v6) 0.8563 Secretion (TM_v5) Secretion (TM_v6) 1 Secretion nucleus 0.169 Secretion mitochondrion 0.064 Secretion plastid 0.0142 Secretion cytoplasm 0.2645 Secretion endoplasmic_reticulum 0.1267 Secretion lysosome_vacuole 0.3012 Secretion golgi_apparatus 0.2787 Secretion peroxisome 0.0249 Secretion peroxisome 0.7627 Secretion extracellular 0.2141 Homology Orthogroup OG0002335 Homology (SCN counts) 2 Homology (BCN counts) 2 Homology (BCN genes) Hsc_gene_1772.t1;Hsc_gene_24108.t1 Homology BCN hits Hsc_gene_1772.t1;Hsc_gene_24106.t1;Hsc_gene_24108.t1 Homology C. elegans hits Homology SP best hit Q7Z408.2 CUB and sushi domain-containing protein 2 [Homo sapiens] Homology NR best hit XP_042930343.1 GCC2 and GCC3 family protein [Brugia malayi];VIO87731.1 GCC2 and GCC3 family protein [Brugia malayi] Homology HGT Donor No Homology HGT Index 0 Functional TF Functional GO terms GO:0005509|GO:0005515 Functional DeepGoPlus GO:0008150_0.843|GO:0005575_0.753|GO:0110165_0.728|GO:0003674_0.703|GO:0009987_0.679|GO:0032501_0.602|GO:0032502_0.576|GO:0048856_0.576|GO:0065007_0.520|GO:0071944_0.519|GO:0050896_0.515|GO:0050789_0.501 Functional InterPro IPR000152+938-949_2413-2424_2489-2500_2527-2538_2568-2579_2606-2617_2773-2784+|IPR000421+1468-1614_1469-1614_1473-1613_1497-1604+|IPR000436+656-720_658-718_721-781_723-779_723-780_782-842_784-840_784-841_861-918_882-918_1218-1278_1220-1276_1220-1277_1352-1419_1354-1417_1354-1418_1422-1469_3167-3237_3169-3235+|IPR000742+920-960_923-960_947-959_1155-1216_2241-2277_2244-2277_2265-2276_2279-2315_2282-2315_2283-2313_2303-2314_2317-2356_2320-2356_2344-2355_2358-2396_2361-2396_2362-2393_2384-2395_2398-2434_2401-2434_2402-2432_2422-2433_2436-2472_2439-2472_2440-2469_2460-2471_2474-2510_2477-2510_2478-2506_2498-2509_2512-2548_2515-2548_2516-2544_2536-2547_2550-2589_2553-2589_2577-2588_2591-2627_2594-2627_2595-2625_2615-2626_2629-2666_2632-2666_2633-2664_2654-2665_2668-2704_2671-2704_2692-2703_2706-2756_2709-2756_2744-2755_2758-2794_2761-2794_2782-2793_3565-3602_3626-3668_3668-3703_3670-3703_3691-3702+|IPR000859+296-405_296-409_303-408_413-520_413-523_524-657+|IPR001304+108-250_115-250_126-251+|IPR001881+920-960_1152-1194_2263-2315_2319-2356_2360-2396_2398-2434_2436-2472_2474-2510_2513-2548_2550-2589_2591-2627_2633-2666_2706-2756_2758-2794_3623-3668+|IPR002172+253-288_253-289_253-290_254-288+|IPR003410+1640-1726_1641-1722_1725-1807_1727-1810_3080-3166+|IPR008979+1469-1615+|IPR009030+2108-2240_2385-2517_2556-2672_2740-3442_3414-3607+|IPR011641+2090-2129_2136-2186_2193-2240_3412-3459_3475-3513_3526-3566_3574-3621+|IPR013032+2250-2271_2567-2583+|IPR013320+2816-3002+|IPR016186+59-255+|IPR016187+103-254+|IPR018097+920-947_2398-2422_2474-2498_2758-2782+|IPR023415+266-288+|IPR035914+292-410_295-409_411-522_412-521_523-656_523-657+|IPR035976+657-732_721-785_783-854_1215-1278_1353-1424+|IPR036055+248-289_256-285+|IPR049883+920-955_1152-1184+ Functional SMART SM00032+658-718_723-779_784-840_861-918_1220-1276_1354-1417_1422-1469_3169-3235+|SM00034+108-250+|SM00042+296-409_413-523_524-657+|SM00179+920-960_1152-1194_2263-2315_2319-2356_2360-2396_2398-2434_2436-2472_2474-2510_2513-2548_2550-2589_2591-2627_2633-2666_2706-2756_2758-2794_3623-3668+|SM00181+923-960_1155-1216_2244-2277_2282-2315_2320-2356_2361-2396_2401-2434_2439-2472_2477-2510_2515-2548_2553-2589_2594-2627_2632-2666_2671-2704_2709-2756_2761-2794_3565-3602_3626-3668_3670-3703+|SM00192+253-290+|SM00231+1468-1614+|SM01411+2084-2129_2136-2186_2193-2240_3411-3459_3466-3513_3520-3566_3574-3621+ Functional Pfam PF00008+2283-2313_2362-2393_2402-2432_2440-2469_2478-2506_2516-2544_2595-2625_2633-2664+EGF-like_domain|PF00057+253-288+Low-density_lipoprotein_receptor_domain_class_A|PF00059+126-251+Lectin_C-type_domain|PF00084+723-779_784-840_882-918_1220-1276_1354-1417+Sushi_repeat_(SCR_repeat)|PF00431+296-405_413-520+CUB_domain|PF00754+1497-1604+F5/8_type_C_domain|PF02494+1641-1722_1725-1807+HYR_domain|PF07645+920-955_1152-1184+Calcium-binding_EGF_domain|PF07699+2090-2129_2136-2186_2193-2240_3412-3459_3475-3513_3526-3566_3574-3621+Tyrosine-protein_kinase_ephrin_type_A/B_receptor-like|PF12661+2250-2271_2567-2583+Human_growth_factor-like_EGF Functional FunFam G3DSA:2.10.25.10:FF:000038+915-959+Fibrillin_2|G3DSA:2.10.25.10:FF:000066+2280-2317_2514-2550+FAT_atypical_cadherin_4|G3DSA:2.10.25.10:FF:000117+2399-2437+Delta-like_protein|G3DSA:2.10.25.10:FF:000146+2552-2591+Putative_neurogenic_locus_notch|G3DSA:2.10.25.10:FF:000173+2360-2398+Neurogenic_locus_notch_protein_2|G3DSA:2.10.25.10:FF:000247+2592-2629+Delta/notch_like_EGF_repeat_containing|G3DSA:2.10.25.10:FF:000472+2438-2513_2721-2798+Uncharacterized_protein,_isoform_A|G3DSA:2.10.50.10:FF:000018+2086-2142+Sushi,_von_Willebrand_factor_type_A,_EGF_and_pentraxin_domain-containing_1|G3DSA:2.10.70.10:FF:000014+1218-1277+Membrane_cofactor_protein|G3DSA:2.60.120.290:FF:000005+411-521+Procollagen_C-endopeptidase_enhancer_1 Functional Panther PTHR12916+2223-2687+ Sequence Protein Sequence Structure Disorder regions Structure (regions) 3298-3370;3799-3909 Structure Ordered 2 Structure (regions) 1-3297;3371-3798 Structure PDB 9b3n_A Structure (hit type) PARTIAL_DOMAIN Biophysics Inclusion Body 0.752 Biophysics Mol weight 428853.64 Biophysics pI 5.6365 Biophysics Net Charge -42.5 Biophysics Charged 22.614 Biophysics Aromatic 10.13 Biophysics Polar 45.51 Biophysics Non-polar 54.49 Biophysics Basic 11.307 Biophysics Acidic 11.307 Biophysics Small 56.536 Composition Ala 0.75 Composition Asn 1.071 Composition Asp 0.865 Composition Cys 2.161 Composition Glu 1.091 Composition Gln 1.384 Composition Gly 0.993 Composition His 1.087 Composition Ile 0.807 Composition Leu 0.989 Composition Lys 0.512 Composition Met 0.767 Composition Phe 1.322 Composition Pro 1.392 Composition Arg 1.175 Composition Ser 1.148 Composition Thr 0.797 Composition Val 0.907 Composition Trp 1.004 Composition Tyr 0.557 Composition Xaa 0.0 Expression Bin13 skyblue Expression Bin38 turquoise Expression Average 801.887 Expression Egg 795.361 Expression ppJ2 483.0739 Expression pJ2 327.7855 Expression J3 759.4773 Expression J4 1177.226 Expression Female 927.6905 Expression Male 303.9549 Expression Gland (J2) 88.533 Expression Gland (J3) 1651.3924 Expression Gland (J2+J3) 981.5956 DGE Egg vs ppJ2 -0.9509 DGE Egg vs pJ2 -1.4159 DGE ppJ2 vs pJ2 -0.4494 DGE pJ2 vs J3 1.1801 DGE J3 vs J4 0.6488 DGE J4 vs F -0.335 DGE J4 vs M -2.0684 DGE F vs M 1.755 DGE G(J3 vs J2) -4.3653 DGE G(J2) vs pJ2 DGE G(J3) vs J3 DGE G(J2) lines DGE G(J3) lines